Monthly Archives: August 2017

Personal Health Update

I haven’t written about my health in quite a while because there wasn’t anything positive to share. At the end of 2014 I was feeling fairly good and started taking prerequisite science classes so I could pursue a degree in Human Nutrition. Then my health took a turn for the worse with chronic urinary tract infections that lead to a bladder ulcer. The long term antibiotics to heal the ulcer caused systemic yeast infections and SIBO (small intestine bacterial overgrowth), which significantly impacted my health and increased my fatigue. While my gut health still isn’t where it was prior to the antibiotics, I made a few changes this spring that has improved my fatigue and a few other symptoms plus allowed me to reduce doses on some medications and supplements.

I added a low dose (1000mg) of D-ribose twice a day and saw almost immediate improvements in my fatigue. D-ribose is a sugar molecule required for the production of RNA, DNA, NADH, and ATP. ATP is the major energy currency of cells and is required for proper metabolism. High doses of D-ribose (5g 2-3x a day) has been studied in patients with congestive heart failure and ME/CFS as well as in athletes for recovery from physical activity with fair results, but personal anecdotes from patients with fatigue suggested smaller doses were more effective. Due to inflammation reactions and occasionally asthma attacks from sucrose sugar, starting at a lower dose made the most sense for me. I started at 500mg once a day and over a few weeks increased to 1000mg twice a day (morning and afternoon). I tried 1500mg twice a day and 1000mg three times a day, but saw increases in my inflammation and worsening sleep quality that I didn’t get at 1000mg twice a day. Within weeks my fatigue had improved to the point where I could reduce my CoQ10/Ubiquinol dose from 400mg twice a day to 200mg twice a day and reduce my acetyl l-carnitine from 1000mg twice a day to 500mg twice a day. Within a month I also was able to eliminate Cytomel T-3 only thyroid medication completely and my thyroid hormone levels are stable on levothyroxine alone. Apparently a deficiency in ATP depresses the utilization of iodine required for thyroid hormone production so increasing my ATP production with D-ribose also improved my hypothyroidism. This explains why my hypothyroidism got so much worse when my fatigue became severe and why I had such a hard time balancing my thyroid meds since then.

I added rhodiola rosea twice a day to my treatment plan about a month before I started taking D-ribose. It’s an adaptogen that helps with oxidative stress and fatigue from psychological and physiological stressors. It seems to have helped me with heat stress this summer, though I also increased my salt intake by 1/2 a teaspoon per day added to my water, lemonade, or herbal tea. Increased salt intake has improved my tachycardia by more than 10bpm and reduced the incidents of dehydration I used to get from swimming outdoors in the summer heat.

Another big change in my routine is my eating plan. While I still follow a low carb diet, I began experimenting with intermittent fasting. First I tried 4:3 fasting, which is eating for four days a week and restricting food to no more than 500 calories three days a week. I lost 12lbs in the month I did 4:3 fasting, but it wasn’t very sustainable. I then switched to 18 hour overnight fasts with lunch as my main meal. I fast from about 7pm to 1pm the next day. I’ve lost 8lbs since I’ve been doing it and I plan to continue it. My fasting blood glucose has improved more with intermittent fasting than it did on a low carb diet alone and avoiding type 2 diabetes is a bigger long term goal for me than weight loss. Research suggests that intermittent fasting along with a low carbohydrate diet also improves mitochondrial function.

Below is my current medication/supplement treatment regime:

Myalgia/Sleep Disorders

  • Cyclobenzaprine (generic Flexeril) – 10mg/day at 7pm
  • Naltrexone, Low Dose (LDN) – 3mg/day at 11pm
  • Magnesium Oxide – 1000mg/day; 500mg at 3pm and 11pm
  • Melatonin – 250mcg/day at 11pm
  • Potassium Glutamate – 99mg as needed for leg cramps

Mitochondrial Dysautonomia & Nutrient Deficiencies

  • Acetyl L-Carnitine – 500mg 2x/day at 9am and 3pm
  • Alpha Lipoic Acid – 300mg/day; 150mg at 9am and 3pm
  • Calcium Citrate – 400mg/day at 3pm
  • CoQ10/Ubiquinol – 200mg 2x/day at 9am and 3pm
  • Coenzymated B Complex – 2x/day at 9am and 3pm
  • D-ribose – 1000mg 2x/day at 9am and 3pm
  • Probiotics – 2 tab/day at 9am and 3pm
  • Rhodiola Rosea – 100mg 2x/day at 9am and 3pm
  • Thiamine (coenzymated) – 25mg 2x/day at 7am and 11pm
  • Vitamin D3 – 2000UI/day at 3pm
  • Vitamin K2 (MK-7) – 100mg/day at 3pm

Hypothyroidism

  • Synthroid (levothyroxine) – 75mcg/day at 7am

Other Genetic Mutations (COMT)

  • L-theanine – 100mg 2x/day at 9am and 3pm

Mold/Biotoxin Illness & High Clotting Factor VII

  • Losartan – 25mg/day at 7pm
  • Aged Garlic Extract (Kyolic 100) – 600mg before meals
  • Vitamin C – 150mg/day at 7pm
  • Zinc – 15mg/day at 11pm

Allergies

  • Allertec (generic Zyrtec) – 25mg/day at 11pm
  • Guaifenesin (generic Mucinex) – 400mg 2x/day at 9am and 11pm
  • Immunotherapy vaccines (allergy shots) – every 4 weeks

Liver Issues

  • Milk Thistle – 175mg 2x/day at 9am and 11pm

Perimenopause

  • Chaste tree Vitex – 225mg/day at 11pm
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